A derivative of Hoechst 33258
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Product Categories

Product Type

Biochemicals

Research Area

Cancer
Cell Death

HOE 32021

Item No. 39912

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2′-(4-methoxyphenyl)-6-(4-methyl-1-piperazinyl)-2,6′-bibenzimidazole
CAS Number
23623-06-5
Molecular Formula
C26H26N6O
Formula Weight
438.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
CN1CCN(CC1)C2=CC=C3N=C(C4=CC=C5C(NC(C(C=C6)=CC=C6OC)=N5)=C4)NC3=C2
InChi Code
InChI=1S/C26H26N6O/c1-31-11-13-32(14-12-31)19-6-10-22-24(16-19)30-26(28-22)18-5-9-21-23(15-18)29-25(27-21)17-3-7-20(33-2)8-4-17/h3-10,15-16H,11-14H2,1-2H3,(H,27,29)(H,28,30)
InChi Key
ZEEIKPHYGCYRRH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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Download most recent Certificate of Analysis for this product

    1 mg

    $193

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    Cayman Chemical
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    Product Description

    HOE 32021 is a derivative of the fluorescent DNA probe Hoechst 33258 (Item No. 16756). It is cytotoxic to L1210 murine skin lymphocytic leukemia cells (IC50 = 130 nM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Finlay, G.J., and Baguley, B.C. Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II. Eur. J. Cancer 26(5), 586-589 (1990).