A metabolite of ricinoleic acid
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Product Categories

Product Type

Biochemicals
Lipids
Octadecanoids

Research Area

Neuroscience

12-oxo Stearic Acid

Item No. 40259

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
12-oxo-octadecanoic acid
CAS Number
925-44-0
Synonyms
  • 12-keto Octadecanoic Acid
  • 12-keto Stearic Acid
  • 12-oxo C18:0
  • 12-oxo Octadecanoic Acid
  • NSC 2103
Molecular Formula
C18H34O3
Formula Weight
298.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Soluble
SMILES
CCCCCCC(CCCCCCCCCCC(O)=O)=O
InChi Code
InChI=1S/C18H34O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h2-16H2,1H3,(H,20,21)
InChi Key
OFOWUDSDZLONKT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 mg

    $171

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    50 mg

    $325

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    100 mg

    $614

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    Product Description

    12-oxo Stearic acid is a saturated oxo fatty acid (SOFA) and metabolite of ricinoleic acid (Item No. 10009369) that has been found in cow and goat milk.1,2 Dietary administration of 12-oxo stearic acid (0.25%) induces encephalomalacia in chicks fed a vitamin E-deficient diet.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Alves, S.P., Araujo, C.M., Queiroga, R.C., et al. New insights on the metabolism of ricinoleic acid in ruminants. J. Dairy Sci. 100(10), 8018-8032 (2017).

    2. Kokotou, M.G., Batsika, C.S., Mantzourani, C., et al. Free saturated oxo fatty acids (SOFAs) and ricinoleic acid in milk determined by a liquid chromatography-high-resolution mass spectrometry (LC-HRMS) method. Metabolites 11(1), 46 (2021).

    3. Kokatnur, M.G., Okui, S., Kummerow, F.A., et al. Effect of long chain keto acids on encephalomalacia in chicks. Proc. Soc. Exp. Biol. Med. 104, 170-171 (12/05/2023).