A cognate dye ligand for the Pepper RNA aptamer
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HBC 530

Item No. 40295

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-benzeneacetonitrile
CAS Number
156840-13-0
Molecular Formula
C19H17N3O
Formula Weight
303.4
Purity
≥98%
Emission
530 nm
Excitation
485 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
N#CC1=CC=C(C(C#N)=CC2=CC=C(N(CCO)C)C=C2)C=C1
InChi Code
InChI=1S/C19H17N3O/c1-22(10-11-23)19-8-4-15(5-9-19)12-18(14-21)17-6-2-16(13-20)3-7-17/h2-9,12,23H,10-11H2,1H3
InChi Key
DIAVZHWDYXQAFC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $28

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    5 mg

    $125

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    10 mg

    $180

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    25 mg

    $413

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    Product Description

    HBC 530 is a cognate dye ligand for the Pepper RNA aptamer.1,2 Upon binding to the Pepper RNA aptamer, the Pepper-HBC 530 complex displays excitation/emission maxima of 485/530 nm, respectively.2 HBC 530 has been used in the live cell imaging of RNA.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huang, K., Chen, X., Li, C., et al. Structure-based investigation of fluorogenic Pepper aptamer. Nat. Chem. Biol. 17(12), 1289-1295 (2021).

    2. Chen, X., Zhang, D., Su, N., et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat. Biotechnol. 37(11), 1287-1293 (2019).