An azido-reactive click-chemistry reagent
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Reactive Probes

Research Area

Cancer

Application

Click Chemistry

DBCO-NHS ester

Item No. 40461

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11,12-didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS Number
1353016-71-3
Synonyms
  • DBCO N-hydroxysuccinimide ester
  • DIBAC N-hydroxysuccinimide ester
  • DIBAC-NHS ester
  • Dibenzocyclooctyne N-hydroxysuccinimide ester
Molecular Formula
C23H18N2O5
Formula Weight
402.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: SolubleDMSO: Soluble
SMILES
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(ON(C4=O)C(CC4)=O)=O
InChi Code
InChI=1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
InChi Key
XCEBOJWFQSQZKR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $109

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    50 mg

    $196

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    100 mg

    $283

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    250 mg

    $545

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    Cayman Chemical
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    Product Description

    DBCO-NHS ester is an azido-reactive click-chemistry reagent.1 It has been conjugated to various anticancer agents for targeting azido-labeled cancer cells in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, H., Wang, R., Cai, K., et al. Selective in vivo metabolic cell-labeling-mediated cancer targeting. Nat. Chem. Biol. 13(4), 415-424 (2017).