An ionizable cationic lipid
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BAmP-O16B

Item No. 40473

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(4-(3-((3-(2-(dodecyldisulfaneyl)ethoxy)-3-oxopropyl)amino)propyl)piperazin-1-yl)propyl)azanediyl)dipropionate
Molecular Formula
C61H120N4O6S6
Formula Weight
1198.0
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleDichloromethane: Soluble
SMILES
CCCCCCCCCCCCSSCCOC(CCN(CCC(OCCSSCCCCCCCCCCCC)=O)CCCN1CCN(CCCNCCC(OCCSSCCCCCCCCCCCC)=O)CC1)=O
InChi Code
InChI=1S/C61H120N4O6S6/c1-4-7-10-13-16-19-22-25-28-31-53-72-75-56-50-69-59(66)36-40-62-39-34-41-64-46-48-65(49-47-64)43-35-42-63(44-37-60(67)70-51-57-76-73-54-32-29-26-23-20-17-14-11-8-5-2)45-38-61(68)71-52-58-77-74-55-33-30-27-24-21-18-15-12-9-6-3/h62H,4-58H2,1-3H3
InChi Key
ONNUDORABXGDRF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    5 mg

    $130

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    10 mg

    $247

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    25 mg

    $585

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    Cayman Chemical
    Ionizable Lipids – Your Path from R&D to GMP

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    Product Description

    BAmP-O16B is an ionizable cationic amino lipid that has been used in the generation of lipid nanoparticles (LNPs).1 LNPs containing BAmP-O16B and encapsulating NSA-inactivated RNase A reduce the viability of SiHa and HeLa cancer cells, but not non-cancerous NIH3T3 and HEK293T cells, upon intracellular reactivation of RNase A by glutathione (GSH).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zheng, Q., Ma, T., and Wang, M. Unleashing the power of proenzyme delivery for targeted therapeutic applications using biodegradable lipid nanoparticles. Acc. Chem. Res. 57(2), 208-221 (2024).