An ionizable cationic lipid
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Lipid DIM1

Item No. 40512

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1',1'',1'''-(((((3R,3aS,6S,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl)bis(oxy))bis(propane-3,1-diyl))bis(azanetriyl))tetrakis(dodecan-2-ol)
CAS Number
2820155-36-8
Molecular Formula
C60H120N2O8
Formula Weight
997.6
Purity
≥95%
Formulation (Request formulation change)
A 50 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Chloroform: Sparingly soluble: 1-10 mg/mlEthanol: Soluble: ≥10 mg/mlMethanol: Slightly soluble: 0.1-1 mg/ml
SMILES
OC(CCCCCCCCCC)CN(CC(O)CCCCCCCCCC)CCCO[C@H]1[C@@](OC2)([H])[C@](OC1)([H])[C@H]2OCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
InChi Code
InChI=1S/C60H120N2O8/c1-5-9-13-17-21-25-29-33-39-53(63)47-61(48-54(64)40-34-30-26-22-18-14-10-6-2)43-37-45-67-57-51-69-60-58(52-70-59(57)60)68-46-38-44-62(49-55(65)41-35-31-27-23-19-15-11-7-3)50-56(66)42-36-32-28-24-20-16-12-8-4/h53-60,63-66H,5-52H2,1-4H3/t53?,54?,55?,56?,57-,58+,59-,60-/m0/s1
InChi Key
YTDBTDJNDXVDHF-WZLTYCDFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $83

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    25 mg

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    50 mg

    $310

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    Cayman Chemical
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    Product Description

    Lipid DIM1 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vitro.1 LNPs containing lipid DIM1 and encapsulating mRNA encoding a luciferase reporter induce luminescence in primary mouse adipose stem cells (ASCs).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Xue, Y., Zhang, Y., Zhong, Y., et al. LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. Nat. Commun. 15(1), 739 (2024).