A Kv7.2 activator
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Ebio1

Item No. 40604

Technical Information
Formal Name
N-(1,2-dihydro-5-acenaphthylenyl)-4-fluoro-benzamide
CAS Number
339287-36-4
Molecular Formula
C19H14FNO
Formula Weight
Purity
≥98%
Formulation
A solid
DMSO: SolubleMethanol: Soluble
SMILES
O=C(C1=CC=C(C=C1)F)NC2=CC=C3C4=C(CC3)C=CC=C42
InChi Code
InChI=1S/C19H14FNO/c20-15-9-6-14(7-10-15)19(22)21-17-11-8-13-5-4-12-2-1-3-16(17)18(12)13/h1-3,6-11H,4-5H2,(H,21,22)
InChi Key
VROYHHCUXRMIQY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ebio1 is an activator of the voltage-gated potassium channel Kv7.2.1 It enhances voltage-induced current amplitude in CHO cells expressing recombinant human Kv7.2 when used at a concentration of 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, S., Ma, D., Wang, K., et alA small-molecule activation mechanism that directly opens the KCNQ2 channel. Nat. Chem. Biol. (2024).