A fungal metabolite with angiogenic activity
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2-((2-Hydroxypropionyl)amino)benzamide

Item No. 40915

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(2-hydroxy-1-oxopropyl)amino]-benzamide
CAS Number
18326-27-7
Synonyms
  • N-(2-hydroxypropanoyl)-2-Aminobenzoic Acid Amide
Molecular Formula
C10H12N2O3
Formula Weight
208.2
Purity
≥70%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
O=C(C1=C(NC(C(C)O)=O)C=CC=C1)N
InChi Code
InChI=1S/C10H12N2O3/c1-6(13)10(15)12-8-5-3-2-4-7(8)9(11)14/h2-6,13H,1H3,(H2,11,14)(H,12,15)
InChi Key
GDRIDNGVFSNDEM-UHFFFAOYSA-N
Origin
Bacterium/Penicillium atrovenetum
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $274

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    Product Description

    2-((2-Hydroxypropionyl)amino)benzamide is a fungal metabolite that has been found in Penicillium and has angiogenic activity.1 It induces angiogenesis in a zebrafish larval model of vascular insufficiency induced by the VEGFR inhibitor PTK787 (vatalanib; Item No. 14868) when added to the tank water at a concentration of 100 µg/ml.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, P., Xie, D., Chen, H., et al. Secondary metabolites from marine derived fungus Penicillium chrysogenum Y19-1 with proangiogenic and antithrombotic activities. Biochem. Syst. Ecol. 107, 104625 (2023).