Naveni CD8/MHC-I Atto647N

The Naveni® CD8/MHC-I Atto647N is an in situ proximity ligation assay kit for the detection of the interaction of CD8 and MHC-I. This in situ kit gives a high signal-to-noise ratio and has outstanding specificity. The kit is compatible with immunofluorescence co-staining for visualization of the tumor microenvironment. The kit has been validated on FFPE human tissue samples. Not recommend for mouse tissue.

The kit is based on our Naveni™ in situ Proximity Ligation Technology, featuring two Navenibodies linked to proprietary oligo arms.The technology ensures precise and sensitive detection; learn more about Naveni technology. The primary antibodies included in the kit bind to CD8 and MHC-I proteins, while Navenibodies then bind to their respective primary antibodies. When Navenibodies are in close proximity, a strong and distinct signal is generated, offering a specific and sensitive detection method for the interaction between CD8 and MHC-I.

Included in the kit:
• Primary antibody targeting human CD8
• Primary antibody targeting human MHC-I
• Two Navenibodies targeting respectively primary antibody
• Detection fluorophore; Atto647N
• Buffers for blocking and dilutions, and all detection reagents
• The Navenibody solution has a working volume of 4000 µl

Tris EDTA antigen retrieval buffer pH 9, wash buffer, DAPI nuclear stain, and mounting medium are not included in the kit.

WARNING This product is not for human or veterinary use.