A TAAR1 agonist
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Ralmitaront

Item No. 41111

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-ethyl-4-methyl-N-[4-(2S)-2-morpholinylphenyl]-1H-pyrazole-3-carboxamide
CAS Number
2133417-13-5
Synonyms
  • RG-7906
  • RO6889450
Molecular Formula
C17H22N4O2
Formula Weight
314.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Sparingly Soluble: 1-10 mg/ml
SMILES
O=C(C1=NNC(CC)=C1C)NC2=CC=C([C@H]3CNCCO3)C=C2
InChi Code
InChI=1S/C17H22N4O2/c1-3-14-11(2)16(21-20-14)17(22)19-13-6-4-12(5-7-13)15-10-18-8-9-23-15/h4-7,15,18H,3,8-10H2,1-2H3,(H,19,22)(H,20,21)/t15-/m1/s1
InChi Key
XHHXGKRFUPEPFM-OAHLLOKOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $124

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    5 mg

    $370

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    10 mg

    $555

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    Product Description

    Ralmitaront is an agonist of trace amine-associated receptor 1 (TAAR1).1 It induces cAMP accumulation in HEK293T cells expressing human TAAR1 (EC50 = 17.78 nM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ågren , R., Betari, N., Saarinen, M., et al. In vitro comparison of ulotaront (SEP-363856) and ralmitaront (RO6889450): Two TAAR1 agonist candidate antipsychotics. Int. J. Neuropsychopharmacol. 26(9), 599-606 (2023).