A SMOX inhibitor
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JNJ-9350

Item No. 41171

Technical Information
Formal Name
N-[3-(1H-imidazol-1-yl)propyl]-5,7-diphenyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS Number
326923-09-5
Molecular Formula
C25H22N6O
Formula Weight
Purity
≥98%
Formulation
A solid
DMSO: Sparingly soluble: 1-10 mg/mlMethanol: Slightly soluble: 0.1-1 mg/ml
SMILES
O=C(C1=NN2C(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=NC2=C1)NCCCN5C=NC=C5
InChi Code
InChI=1S/C25H22N6O/c32-25(27-12-7-14-30-15-13-26-18-30)22-17-24-28-21(19-8-3-1-4-9-19)16-23(31(24)29-22)20-10-5-2-6-11-20/h1-6,8-11,13,15-18H,7,12,14H2,(H,27,32)
InChi Key
RIGHCDSORZCRDE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    JNJ-9350 is an inhibitor of spermine oxidase (SMOX; IC50 = 10 µM).1 It is selective for SMOX over polyamine oxidase (PAOX; IC50 = 739 µM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cros, J.L., Viturro, C.M.M., Lamenca, C.M., et alPyrazolopyrrimidines as modulators of spermine oxidase. (2023).