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N-desethyl Fluetonitazene (hydrochloride)

Item No. 41296

Synonyms
Synonyms
  • DFNZ
  • N-desethyl Fluornitrazene
Technical Information
Formal Name
N-ethyl-2-(2-(4-(2-fluoroethoxy)benzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)ethan-1-amine
Molecular Formula
C20H23FN4O3 • HCl
Formula Weight
Purity
≥98%
A solid
DMSO: Soluble: ≥10mg/ml
SMILES
CCNCCN1C(CC2=CC=C(OCCF)C=C2)=NC3=C1C=CC([N+]([O-])=O)=C3.Cl
InChi Code
InChI=1S/C20H23FN4O3.ClH/c1-2-22-10-11-24-19-8-5-16(25(26)27)14-18(19)23-20(24)13-15-3-6-17(7-4-15)28-12-9-21;/h3-8,14,22H,2,9-13H2,1H3;1H
InChi Key
RFAQSDQMMINHFK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-desethyl Fluetonitazene (DFNZ) (hydrochloride) (Item No. 41296) is an analytical reference standard categorized as an opioid.1 DFNZ is an active metabolite of fluetonitazene (FNZ; Item No. 40834) that acts as a highly potent μ-opioid receptor agonist. It produces analgesia in rodent models of acute and chronic pain without inducing respiratory depression, tolerance, or μ-opioid receptor downregulation after repeated dosing. DFNZ also has weaker reinforcing effects and increases dopamine neuron activity more slowly and to a lesser extent than FNZ in rodents. This product is intended for research and forensic applications.. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gomez, J.L., Ventriglia, E.N., Frangos, Z.J., et alA µ-opioid receptor superagonist analgesic with minimal adverse effects. Nature 652(8112), 1393-1404 (2026).