A GLP-1R agonist
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GLP-1R Agonist 2

Item No. 41319

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[[(2S)-4-[6-[(4-chloro-2-fluorophenyl)methoxy]-2-pyridinyl]-2-methyl-1-piperazinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid
CAS Number
2230197-64-3
Synonyms
  • GLP-1 Receptor Agonist 2
  • Glucagon-like Peptide 1 Receptor Agonist 2
Molecular Formula
C30H31ClFN5O4
Formula Weight
580.1
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Sparingly soluble: 1-10 mg/mlDMSO: Sparingly soluble: 1-10 mg/ml
SMILES
FC(C=C(C=C1)Cl)=C1COC2=NC(N3C[C@H](C)N(CC4=NC5=CC=C(C(O)=O)C=C5N4C[C@@H]6CCO6)CC3)=CC=C2
InChi Code
InChI=1S/C30H31ClFN5O4/c1-19-15-36(27-3-2-4-29(34-27)41-18-21-5-7-22(31)14-24(21)32)11-10-35(19)17-28-33-25-8-6-20(30(38)39)13-26(25)37(28)16-23-9-12-40-23/h2-8,13-14,19,23H,9-12,15-18H2,1H3,(H,38,39)/t19-,23-/m0/s1
InChi Key
IGXAOFNNKAUXCJ-CVDCTZTESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $109

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    5 mg

    $491

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    Product Description

    GLP-1R agonist 2 is a glucagon-like peptide 1 receptor agonist.1 It induces cAMP accumulation in CHO cells expressing human GLP-1R (EC50 = 0.28 nM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aspnes, G.E., Bagley, S.W., Curto, J.M., et al. GLP-1 receptor agonists and uses thereof. (2018).