An oxidized phospholipid
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1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC

Item No. 41445

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7R,17Z,19E,21S)-4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacosa-17,19-dien-1-aminium, inner salt, 4-oxide
CAS Number
161923-56-4
Synonyms
  • 1-Hexadecanoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine
  • 13(S)-Hydroxyoctadecadienoic Acid-PLPC
  • 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine
  • 1-Palmitoyl-2-(13-hydroxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine
Molecular Formula
C42H80NO9P
Formula Weight
774.1
Purity
≥95%
Formulation (Request formulation change)
A 500 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Slightly Soluble: 0.1-1 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCC/C=C\C=C\[C@H](CCCCC)O)=O)COP(OCC[N+](C)(C)C)([O-])=O
InChi Code
InChI=1S/C42H80NO9P/c1-6-8-10-11-12-13-14-15-16-19-22-25-29-33-41(45)49-37-40(38-51-53(47,48)50-36-35-43(3,4)5)52-42(46)34-30-26-23-20-17-18-21-24-28-32-39(44)31-27-9-7-2/h21,24,28,32,39-40,44H,6-20,22-23,25-27,29-31,33-38H2,1-5H3/b24-21-,32-28+/t39-,40+/m0/s1
InChi Key
YRNDWGBUIFZEKZ-CZPAHNRFSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    50 µg

    $129

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    100 µg

    $233

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    500 µg

    $901

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    Product Description

    1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC is an oxidized phospholipid that contains palmitic acid (Item No. 10006627) and 13(S)-HODE (Item No. 38610) at the sn-1 and sn-2 positions, respectively. It has been used to detect the activity of glutathione peroxidase 4 (GPX4), also known as phospholipid hydroperoxide glutathione peroxidase (PhGPx), using 1-palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC (Item No. 31976) as the substrate.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bao, Y., Chambers, S.J., and Williamson, G. Direct separation of hydroperoxy- and hydroxy-phosphatidylcholine derivatives: Application to the assay of phospholipid hydroperoxide glutathione peroxidase. Anal. Biochem. 224(1), 395-399 (1995).