An acid form of α-MSH
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α-MSH Acid (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Item No. 41463

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
13-L-valine-α-melanotropin, trifluoroacetate salt
Synonyms
  • N-acetyl ACTH (1-13)
  • N-acetyl Adrenocorticotropic Hormone (1-13)
  • α-Melanocyte-stimulating Hormone Acid
  • α-MSH-OH
Molecular Formula
C77H108N20O20S • XCF3COOH
Formula Weight
1665.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Peptide Sequence
Ac-SYSMEHFRWGKPV-OH
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC(C)=O)=O)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C77H108N20O20S.C2HF3O2/c1-42(2)64(76(116)117)96-74(114)61-20-13-30-97(61)75(115)54(18-10-11-28-78)87-62(102)38-84-65(105)57(34-46-36-83-50-17-9-8-16-49(46)50)93-66(106)51(19-12-29-82-77(79)80)88-69(109)55(32-44-14-6-5-7-15-44)91-71(111)58(35-47-37-81-41-85-47)94-67(107)52(25-26-63(103)104)89-68(108)53(27-31-118-4)90-73(113)60(40-99)95-70(110)56(33-45-21-23-48(101)24-22-45)92-72(112)59(39-98)86-43(3)100;3-2(4,5)1(6)7/h5-9,14-17,21-24,36-37,41-42,51-61,64,83,98-99,101H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H,81,85)(H,84,105)(H,86,100)(H,87,102)(H,88,109)(H,89,108)(H,90,113)(H,91,111)(H,92,112)(H,93,106)(H,94,107)(H,95,110)(H,96,114)(H,103,104)(H,116,117)(H4,79,80,82);(H,6,7)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-;/m0./s1
InChi Key
QWXHYVQTXKDJNP-VLZMNQITSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    100 mg

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    250 mg

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    Product Description

    α-Melanocyte-stimulating hormone (α-MSH) acid is an acid form of α-MSH (Item No. 29923).1 It selectively binds to melanocortin receptor 1 (MC1R) over MC3R, MC4R, and MC5R in COS-1 cells expressing the human receptors (Kis = 0.0012, 0.0829, 3.05, and 18.2 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Schiöth, H.B., Muceniece, R., Larsson, M., et al. The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of α-MSH. J. Endocrinol. 155(1), 73-78 (1997).