A derivative of L-phenylalanine and a click chemistry reagent
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4-Azido-L-phenylalanine

Item No. 41697

Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
33173-53-4
Synonyms
  • para-Azido-L-phenylalanine
  • p-Azido-L-phenylalanine
Molecular Formula
C9H10N4O2
Formula Weight
206.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Sparingly soluble: 1-10 mg/ml
SMILES
OC([C@@H](N)CC1=CC=C(C=C1)N=[N+]=[N-])=O
InChi Code
InChI=1S/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/m0/s1
InChi Key
NEMHIKRLROONTL-QMMMGPOBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $105

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    250 mg

    $236

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    500 mg

    $340

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    1 g

    $627

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    Product Description

    4-Azido-L-phenylalanine is a derivative of the essential amino acid L-phenylalanine (Item No. 31498) and a click chemistry reagent.1,2 It has been used as a photocrosslinking agent and in spin labeling for the assessment of protein-protein interactions in vitro and in vivo.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chin, J.W., Santoro, S.W., Martin, A.B., et al. Addition of p-azido-L-phenylalanine to the genetic code of Escherichia coli. J. Am. Chem. Soc. 124(31), 9026-9027 (2002).

    2. Kucher, S., Korneev, S., Tyagi, S., et al. Orthogonal spin labeling using click chemistry for in vitro and in vivo applications. J. Magn. Reson. 275, 38-45 (2017).