An antidepressant
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Minaprine (hydrochloride)

Item No. 41710

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(4-methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine, dihydrochloride
CAS Number
25905-77-5
Synonyms
  • Agr 1240
  • AG-620
Molecular Formula
C17H22N4O • 2HCl
Formula Weight
371.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
SMILES
CC(C=C(C1=CC=CC=C1)N=N2)=C2NCCN3CCOCC3.Cl.Cl
InChi Code
InChI=1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H
InChi Key
GNUCGROXDZMCJI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $87

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    250 mg

    $207

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    500 mg

    $392

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    Product Description

    Minaprine is an antidepressant.1 It reduces immobility time in the forced swim test in rats when administered at a dose of 5 mg/kg for nine days. Minaprine (40 mg/kg) induces convulsions in rats.2 Formulations containing minaprine have previously been used in the treatment of depression.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Imperato, A., Obinu, M.C., Cabib, S., et al. Effects of subchronic minaprine on dopamine release in the ventral striatum and on immobility in the forced swimming test. Neurosci. Lett. 166(1), 69-72 (1994).

    2. Warter, J.M., Tranchant, C., Marescaux, C., et al. Immediate effects of 14 non MAOI antidepressants in rats with spontaneous petit mal-like seizures. Prog. Neuropsychopharmacol. Biol. Psychiatry 14(2), 261-270 (1990).