A histamine H2 receptor agonist
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Isomer(s)
33828Histamine
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Betazole (hydrochloride)

Item No. 41712

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1H-pyrazole-3-ethanamine, dihydrochloride
CAS Number
138-92-1
Synonyms
  • Ametazole
  • Gastramine
Molecular Formula
C5H9N3 • 2HCl
Formula Weight
184.1
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
NCCC1=NNC=C1.Cl.Cl
InChi Code
InChI=1S/C5H9N3.2ClH/c6-3-1-5-2-4-7-8-5;;/h2,4H,1,3,6H2,(H,7,8);2*1H
InChi Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $54

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    10 mg

    $103

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    50 mg

    $351

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    100 mg

    $647

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    Product Description

    Betazole is a histamine H2 receptor agonist.1 It induces acid secretion in isolated human gastric glands (EC50 = 120 µM), an effect mediated by histamine H2 receptors. Betazole (3-10 mg/kg) increases pepsin and acid levels in gastric juice in dogs.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Leth, R., Elander, B., Haglund, U., et al. Histamine H2-receptor of human and rabbit parietal cells. Am. J. Physiol. 253(Pt. 1), G497-G501 (1987).

    2. Ishimori, A., Sakurada, H., Kawamura, T., et al. Comparison of dose-response curves between acid and pepsin to betazole hydrochloride in the dog with gastric fistula. Gastroenterol. Jpn. 10(3), 221-224 (1975).