A cell-permeable Fe2+-binding fluorescent probe
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FerroOrange

Item No. 41725

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Purity
≥90%
Emission
580 nm
Excitation
543 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
Shipping & Storage Information
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 tube

    $174

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    3 tubes

    $402

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    Cayman Chemical
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    Product Description

    FerroOrange is a cell-permeable fluorescent probe that binds irreversibly to ferrous iron (Fe2+).1 It is selective for Fe2+ over 12 other metal ions. When bound to Fe2+, FerroOrange displays excitation/emission maxima of 540/585 nm, respectively. Monitoring iron levels in cells has high relevance to various cellular processes, especially ferroptosis, which is an iron-dependent form of cell death.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Grubwieser, P., Brigo, N., Seifert, M., et al. Quantification of macrophage cellular ferrous Iron (Fe2+) content using a highly specific fluorescent probe in a plate reader. Bio. Protoc. 14(3), e4929 (2024).

    2. Angeli, J.P.F., Miyamoto, S., and Schulze, A. Ferroptosis: The greasy side of cell death. Chem. Res. Toxicol. 32, 362-369 (2019).