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Mito-FerroGreen is a cell-permeable fluorescent probe that binds irreversibly to mitochondrial ferrous iron (Fe2+). It is selective for Fe2+ over 12 other metal ions. When bound to Fe2+, Mito-FerroGreen displays excitation and emission maxima of 505 and 535 nm, respectively. Monitoring iron levels in cells has high relevance to various cellular processes, especially ferroptosis, which is an iron-dependent form of cell death.1,2
WARNING This product is not for human or veterinary use.
1. Ferroptosis: The greasy side of cell death. Chem. Res. Toxicol. 32, 362-369 (2019).
2. Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis. Virol. J. 20(1), 242 (2023).