A peptide derivative of α-MSH and a synthetic intermediate
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(D-Phe7)-α-MSH (trifluoroacetate salt)

Item No. 41730

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4S,7S,10R,13S,16S,22S)-7-((1H-imidazol-5-yl)methyl)-16-((1H-indol-3-yl)methyl)-26-amino-22-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-10-benzyl-13-(3-guanidinopropyl)-4-((2S,5S,8S,11S)-8-(4-hydroxybenzyl)-5,11-bis(hydroxymethyl)-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanamido)-5,8,11,14,17,20-hexaoxo-6,9,12,15,18,21-hexaazahexacosanoic acid, trifluoroacetate salt
Synonyms
  • (D-Phe7)-α-Melanocyte-stimulating Hormone
Molecular Formula
C77H109N21O19S • XCF3COOH
Formula Weight
1664.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Peptide Sequence
Ac-SYSMEHfRWGKPV-NH2
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC(C)=O)=O)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)C(C)C)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O.FC(F)(F)C(O)=O
InChi Code
InChI=1S/C77H109N21O19S.C2HF3O2/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101;3-2(4,5)1(6)7/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83);(H,6,7)/t51-,52-,53-,54-,55+,56-,57-,58-,59-,60-,61-,64-;/m0./s1
InChi Key
FEOXCJFWEWYJIH-KOSDVYQCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $98

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    5 mg

    $318

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    10 mg

    $539

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    Product Description

    (D-Phe7)-α-Melanocyte-stimulating hormone ((D-Phe7)-α-MSH) is a peptide derivative of α-MSH (Item No. 29923) and an intermediate in the synthesis of α-MSH cyclic analogs.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nikiforovich, G.V., Sharma, S.D., Hadley, M.E., et al. Studies of conformational isomerism in alpha-melanocyte stimulating hormone by design of cyclic analogues. Biopolymers 46(3), 155-167 (1998).