An ionizable cationic lipid
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CP-LC-1428

Item No. 41924

Technical Information
Formal Name
6-methylheptyl 7-(2-((3-((2-butyloctyl)oxy)-3-oxopropyl)thio)ethyl)-2-methyl-14-((3-((6-methylheptyl)oxy)-3-oxopropyl)thio)-6,9-dioxo-17-thia-2,5,8-triazaicosan-20-oate
CAS Number
3097638-08-6
Molecular Formula
C53H101N3O8S3
Formula Weight
Purity
≥95%
A 10 mg/ml solution in ethanol
Ethanol: Soluble: ≥10 mg/ml
SMILES
O=C(NCCN(C)C)C(CCSCCC(OCC(CCCC)CCCCCC)=O)NC(CCCCC(CCSCCC(OCCCCCC(C)C)=O)SCCC(OCCCCCC(C)C)=O)=O
InChi Code
InChI=1S/C53H101N3O8S3/c1-9-11-13-18-26-46(25-12-10-2)43-64-52(60)32-41-66-39-30-48(53(61)54-34-35-56(7)8)55-49(57)28-20-19-27-47(67-42-33-51(59)63-37-22-15-17-24-45(5)6)29-38-65-40-31-50(58)62-36-21-14-16-23-44(3)4/h44-48H,9-43H2,1-8H3,(H,54,61)(H,55,57)
InChi Key
KUHIDYRULVDIOR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Lipid CP-LC-1428 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific spleen targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.

    WARNING This product is not for human or veterinary use.