A spin label
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TOAC

Item No. 42097

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-4-carboxy-2,2,6,6-tetramethyl-1-piperidinyloxy
CAS Number
15871-57-5
Synonyms
  • NSC 239127
Molecular Formula
C10H19N2O3
Formula Weight
215.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
SMILES
[O]N1C(CC(C(O)=O)(N)CC1(C)C)(C)C
InChi Code
InChI=1S/C10H19N2O3/c1-8(2)5-10(11,7(13)14)6-9(3,4)12(8)15/h5-6,11H2,1-4H3,(H,13,14)
InChi Key
FCTFGDVLBOGMPH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $39

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    50 mg

    $74

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    100 mg

    $139

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    Product Description

    TOAC is a nitroxyl amino acid and spin label.1,2 It incorporates a stable nitrogen radical into peptide backbones, which allows it to function as an intrinsic reporter during electron paramagnetic resonance (EPR) spectroscopy, and has been used to study peptide structural dynamics.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Corvaja, C., Sartori, E., Toffoletti, A., et al. Interaction between TOAC free radical and photoexcited triplet chromophores linked to peptide templates. Biopolymers 55(6), 486-495 (2000).

    2. Marsh, D. Orientation of TOAC amino-acid spin labels in α-helices and β-strands. J. Magn. Reson. 180(2), 305-310 (2006).