A benzophenone UV filter
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Oxybenzone

Item No. 42170

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2-hydroxy-4-methoxyphenyl)phenyl-methanone
CAS Number
131-57-7
Synonyms
  • Benzophenone-3
  • 2-Hydroxy-4-methoxybenzophenone
  • NSC 7778
Molecular Formula
C14H12O3
Formula Weight
228.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
COC(C=C1O)=CC=C1C(C2=CC=CC=C2)=O
InChi Code
InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
InChi Key
DXGLGDHPHMLXJC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

    $29

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    100 g

    $40

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    250 g

    $86

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    500 g

    $115

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    Product Description

    Oxybenzone is a benzophenone UV filter.1,2,3 Oral administration of oxybenzone (30, 212, or 3,000 µg/kg per day) to pregnant mice reduces mammary cell proliferation and the number of cells expressing estrogen receptor α (ERα) and alters mammary gland morphology in female offspring.1 It induces cognitive impairments in an associative learning protocol with electroshock as a stimulus and increases brain levels of reactive oxygen species (ROS) in zebrafish.2 Oxybenzone (33 and 50 ppm) induces coral bleaching and death when administered in the tank water.3 Formulations containing oxybenzone have been used as sunscreens and as industrial additives to protect textiles, color agents, and plastics from bleaching and UV-induced degradation.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Matouskova, K., Jerry, D.J., and Vandenberg, L.N. Exposure to low doses of oxybenzone during perinatal development alters mammary gland morphology in male and female mice. Reprod. Toxicol. 92, 66-77 (2020).

    2. Moreira, A.L.P., Paiva, W.S., de Souza, A.M., et al. Benzophenone-3 causes oxidative stress in the brain and impairs aversive memory in adult zebrafish. Environ. Toxicol. Pharmacol. 100, 104164 (2023).

    3. DiNardo, J.C., and Downs, C.A. Dermatological and environmental toxicological impact of the sunscreen ingredient oxybenzone/benzophenone-3. J. Cosmet. Dermatol. 17(1), 15-19 (2018).