A chemiluminescent substrate for NanoLuc® luciferase
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Furimazine

Item No. 42176

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2-furanylmethyl)-6-phenyl-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one
CAS Number
1374040-24-0
Synonyms
  • PBI-3939
Molecular Formula
C24H19N3O2
Formula Weight
381.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Sparingly Soluble: 1-10 mg/ml
SMILES
O=C1N(C=C(N2)C3=CC=CC=C3)C(N=C1CC4=CC=CO4)=C2CC5=CC=CC=C5
InChi Code
InChI=1S/C24H19N3O2/c28-24-21(15-19-12-7-13-29-19)26-23-20(14-17-8-3-1-4-9-17)25-22(16-27(23)24)18-10-5-2-6-11-18/h1-13,16,25H,14-15H2
InChi Key
BUFSEVFXVCFYKY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $196

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    10 mg

    $294

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    25 mg

    $490

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    Product Description

    Furimazine is a chemiluminescent substrate of NanoLuc® luciferase.1 It produces light upon the oxidation and subsequent decarboxylation by NanoLuc® luciferase that can be measured at 460 nm. Furimazine has been used in bioluminescence imaging, in vitro assays, and in rodents.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. England, C.G., Ehlerding, E.B., and Cai, W. NanoLuc: A small luciferase is brightening up the field of bioluminescence. Bioconjug. Chem. 27(5), 1175-1187 (2016).