An amino acid-containing building block
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Fmoc-L-Cys(Mmt)-OH

Item No. 42177

Technical Information
Formal Name
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-[(4-methoxyphenyl)diphenylmethyl]-L-cysteine
CAS Number
177582-21-7
Molecular Formula
C38H33NO5S
Formula Weight
Purity
≥98%
A solid
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@H](C(O)=O)CSC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
InChi Code
InChI=1S/C38H33NO5S/c1-43-29-22-20-28(21-23-29)38(26-12-4-2-5-13-26,27-14-6-3-7-15-27)45-25-35(36(40)41)39-37(42)44-24-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35H,24-25H2,1H3,(H,39,42)(H,40,41)/t35-/m0/s1
InChi Key
LOBUWFUSGOYXQX-DHUJRADRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Fmoc-L-Cys(Mmt)-OH is an amino acid-containing building block.1,2 It has been used in the solid-phase synthesis of S-palmitoylated peptide antigens for use in macrophage uptake assays and stapled peptide dual agonists of the glucagon-like peptide 1 receptor (GLP-1R) and cholecystokinin 2 (CCK2) receptor.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nadège, P., Erwann, G., Judith, M.G., et alSolid-phase synthesis of a biotin-labelled thiopalmitoylated myelin proteolipid protein epitope and application in the study of uptake of antigen by macrophages. Int. J. Pept. Res. Ther. 10, 581-588 (2003).

    2. Chen, X., Fu, J., Zhou, F., et alStapled and Xenopus glucagon-like peptide 1 (GLP-1)-based dual GLP-1/gastrin receptor agonists with improved metabolic benefits in rodent models of obesity and diabetes. J. Med. Chem. 63(21), 12595-12613 (2020).