A SERT, DAT, and NET inhibitor
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ECSI#6

Item No. 42250

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[2-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)ethyl]-formamide
CAS Number
860456-56-0
Molecular Formula
C18H17NO5
Formula Weight
327.3
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Sparingly soluble: 1-10 mg/mlWater: Slightly soluble: 0.1-1 mg/ml
SMILES
O=CNC(CC1=CC=C2OCOC2=C1)CC3=CC=C4OCOC4=C3
InChi Code
InChI=1S/C18H17NO5/c20-9-19-14(5-12-1-3-15-17(7-12)23-10-21-15)6-13-2-4-16-18(8-13)24-11-22-16/h1-4,7-9,14H,5-6,10-11H2,(H,19,20)
InChi Key
HNEITUUMXZICIV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $61

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    5 mg

    $273

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    Product Description

    ECSI#6 is an inhibitor of the serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET).1 It inhibits serotonin, dopamine, and norepinephrine uptake in HEK293 cells expressing human SERT, DAT, and NET (IC50s = 8, 48.2, and 17 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pifl, C., Nagy, G., Berényi, S., et al. Pharmacological characterization of ecstasy synthesis byproducts with recombinant human monoamine transporters. J. Pharmacol. Exp. Ther. 14(1), 346-354 (2005).