A photocontrollable NO donor
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Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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Product Categories

Product Type

Biochemicals
Nitric Oxide Donors

Research Area

Application

NO-Rosa5

Item No. 42356

Product Insert (PDF)
Technical Information
Formal Name
4-(9-(2-(((4-hydroxyphenyl)(nitroso)amino)methyl)phenyl)-6-morpholino-3H-xanthen-3-ylidene)morpholin-4-ium, monochloride
Synonyms
  • Nitric Oxide-Rosa5
Molecular Formula
C34H33N4O5 • Cl
Formula Weight
613.1
Purity
≥95%
Excitation
530-590 nm
Formulation (Request formulation change)
A solid
SMILES
OC(C=C1)=CC=C1N(N=O)CC(C=CC=C2)=C2C(C(C=C3)=C(O4)C=C3N5CCOCC5)=C6C4=C/C(C=C6)=[N+]7CCOCC\7.[Cl-]
InChi Code
InChI=1S/C34H32N4O5.ClH/c39-28-9-5-25(6-10-28)38(35-40)23-24-3-1-2-4-29(24)34-30-11-7-26(36-13-17-41-18-14-36)21-32(30)43-33-22-27(8-12-31(33)34)37-15-19-42-20-16-37;/h1-12,21-22H,13-20,23H2;1H
InChi Key
XNRDLZGRQCUWAC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    250 µg

    $468

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    Product Description

    NO-Rosa5 is a photocontrollable nitric oxide (NO) donor for in cellulo and ex vivo use.1 It is composed of the fluorescent dye rosamine, which functions as the light-harvesting group, and the NO-releasing moiety N-nitrosoaminophenol. Upon excitation of rosamine between 530-590 nm, photoinduced electron transfer from the NO-releasing moiety occurs, forming an unstable phenoxy radical. This radical then releases NO to form a stable quinoneimine product.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ieda, N., Hotta, Y., Kawaguchi, M., et al. In cellullo and ex vivo availability of a yellowish-green-light-controllable no releaser. Chem. Pharm. Bull. 67(6), 579-579 (2019).