An antioxidant, antibacterial, and antifungal agent
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Octyl Gallate

Item No. 42586

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4,5-trihydroxy-benzoic acid, octyl ester
CAS Number
1034-01-1
Synonyms
  • Gallic Acid octyl ester
  • NSC 97419
  • n-Octyl Gallate
  • OG
Molecular Formula
C15H22O5
Formula Weight
282.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
O=C(C1=CC(O)=C(C(O)=C1)O)OCCCCCCCC
InChi Code
InChI=1S/C15H22O5/c1-2-3-4-5-6-7-8-20-15(19)11-9-12(16)14(18)13(17)10-11/h9-10,16-18H,2-8H2,1H3
InChi Key
NRPKURNSADTHLJ-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 g

    $28

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    10 g

    $50

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    25 g

    $97

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    50 g

    $152

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    Cayman Chemical
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    Product Description

    Octyl gallate is an antioxidant, antibacterial, and antifungal agent.1,2 It scavenges free radicals in a Trolox equivalent absorbance capacity (TEAC) assay when used at a concentration of 10 µM.1 Octyl gallate is active against nine bacterial species (MICs = 12.5-50 µg/ml) and the fungi S. cerevisiae, Z. bailii, C. albicans, and A. niger (MICs = 25, 50, 25, and 50 µg/ml, respectively).2 It also inhibits the proliferation of WEHI-231 mouse B cell lymphoma cells (IC50 = 1.5 µM).3 Formulations containing octyl gallate have been used as food additives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wolf, V.G., Bonacorsi, C., Raddi, M.S.G., et al. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. Food Funct. 8(7), 2500-2511 (2017).

    2. Kubo, I., Fujita, K.-i., Nihei, K.-i., et al. Non-antibiotic antibacterial activity of dodecyl gallate. Bioorg. Med. Chem. 11(4), 573-580 (2003).

    3. Serrano, A., Palacios, C., Roy, G., et al. Derivatives of gallic acid induce apoptosis in tumoral cell lines and inhibit lymphocyte proliferation. Arch. Biochem. Biophys. 350(1), 49-54 (1998).