A nitrobenzofurazan
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NBD-Hydrazine

Item No. 42611

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-hydrazinyl-7-nitro-2,1,3-benzoxadiazole
CAS Number
90421-78-6
Synonyms
  • NBDH
  • NBD-H.NH2NH2
Molecular Formula
C6H5N5O3
Formula Weight
195.1
Purity
≥95%
Emission
535 nm
Excitation
468 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
SMILES
NNC(C1=NON=C12)=CC=C2[N+]([O-])=O
InChi Code
InChI=1S/C6H5N5O3/c7-8-3-1-2-4(11(12)13)6-5(3)9-14-10-6/h1-2,8H,7H2
InChi Key
DMZATVKONWVLBE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $28

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    5 mg

    $131

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    10 mg

    $248

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    Product Description

    NBD-hydrazine is an aldehyde- and ketone-reactive fluorescent probe.1 It displays excitation/emission maxima of 468/535 nm, respectively, in the presence of aldehydes or ketones. NBD-hydrazine has also been used as a starting material in the synthesis of malondialdehyde-reactive fluorescent probes and a synthetic intermediate in the synthesis of cupric and chromic ion colorimetric sensors.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Uzu, S., Kanda, S., Imai, K., et al. Fluorogenic reagents: 4-Aminosulphonyl-7-hydrazino2,1,3- benzoxadiazole, 4-( N,N-dimet hylaminosu Ip honyl)-7-hydrazino-2,1,3-enzoxadiazole and 4-hydrazino-7-nitro-2,1,3-benzoxadiazole hydrazine for aldehydes and ketones. Analyst 115, 1477-1482 (1990).

    2. Wang, X., Liu, X., Cheng, T., et al. Development of 4-hydrazinyl-7-nitrobenzofurazan as a fluorogenic probe for detecting malondialdehyde in biological samples. Sens. Actuators B Chem. 254, 248-254 (2018).

    3. S.Y., L., Bok, K.H., Kim, J.A., et al. Simultaneous detection of Cu2+ and Cr3+ by a simple Schiff-base colorimetric chemosensor bearing NBD (7-nitrobenzo-2-oxa-1,3-diazolyl) and julolidine moieties. Tetrahedron 72(35), 5563-5570 (2016).