A GPR3 agonist
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GPR3 Agonist 2

Item No. 42616

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(trifluoromethoxy)-dibenziodolium, 1,1,1-trifluoromethanesulfonate
CAS Number
1983120-51-9
Synonyms
  • G Protein-Coupled Receptor 3 Agonist 2
Molecular Formula
C13H7F3IO • CF3O3S
Formula Weight
512.2
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Slightly soluble: 0.1-1 mg/ml
SMILES
O=S([O-])(C(F)(F)F)=O.FC(F)(OC1=CC([I+]C2=C3C=CC=C2)=C3C=C1)F
InChi Code
InChI=1S/C13H7F3IO.CHF3O3S/c14-13(15,16)18-8-5-6-10-9-3-1-2-4-11(9)17-12(10)7-8;2-1(3,4)8(5,6)7/h1-7H;(H,5,6,7)/q+1;/p-1
InChi Key
RAYXTZAHMQMKFW-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $61

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    5 mg

    $167

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    10 mg

    $273

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    Product Description

    GPR3 agonist 2 is an agonist of G protein-coupled receptor 3 (GPR3).1 It induces cAMP accumulation in HEK293 cells expressing human GPR3 (EC50 = 0.26 µM). It is selective for GPR3 over GPR6 and GPR12 at 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gay, E.A., Harris, D.L., Wilson, J.W., et al. The development of diphenyleneiodonium analogs as GPR3 agonists. Bioorg. Med. Chem. Lett. 94, 129427 (2023).