A ganglioside
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Lyso-Monosialoganglioside GM3 (synthetic)

Item No. 42762

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2S-amino-3R-hydroxy-4E-octadecen-1-yl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside
CAS Number
94458-63-6
Synonyms
  • Lyso-GM3
  • Lysoganglioside GM3
  • lyso-Monosialoganglioside GM3
Molecular Formula
C41H74N2O20
Formula Weight
915.0
Purity
≥98%
Formulation (Request formulation change)
A solution in methanol
Solubility(Learn about Variance in Solubility)
Methanol: Slightly Soluble: 0.1-1 mg/ml
SMILES
O[C@@H]([C@@H](O[C@H](CO)[C@H]1O[C@H]2[C@H](O)[C@@H](O[C@]3(O[C@@]([C@@H]([C@@H](O)C3)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O)[C@H]([C@H](O2)CO)O)OC[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)N)[C@H]1O
InChi Code
InChI=1S/C41H74N2O20/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24(48)23(42)21-58-38-33(54)32(53)35(28(20-46)60-38)61-39-34(55)37(31(52)27(19-45)59-39)63-41(40(56)57)17-25(49)29(43-22(2)47)36(62-41)30(51)26(50)18-44/h15-16,23-39,44-46,48-55H,3-14,17-21,42H2,1-2H3,(H,43,47)(H,56,57)/b16-15+/t23-,24+,25-,26+,27+,28+,29+,30+,31-,32+,33+,34+,35+,36+,37-,38+,39-,41-/m0/s1
InChi Key
QLMGGRZACLACKO-PJSUIWAYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $798

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Lyso-monosialoganglioside GM3 (Lyso-GM3) is a form of ganglioside GM3 (Item Nos. 31711 | 15587) that is lacking the fatty acyl group.1 It inhibits EGF-induced increases in EGFR kinase activity in A431 epithelial cancer cells when used at a concentration of 500 µM. This product is fully synthetic and has no variations in the sphingoid backbone.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanai, N., Nores, G., Torres-Méndez, C.R., et al. Modified ganglioside as a possible modulator of transmembrane signaling mechanism through growth factor receptors: A preliminary note. Biochem. Biophys. Res. Commun. 147(1), 127-134 (1987).