For immunochemical detection of MUC17
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

MUC17 Rabbit Monoclonal Antibody (Clone RM517)

Item No. 42783

Product Insert (PDF)
Technical Information
Synonyms
  • Mucin 17
Immunogen
Peptide corresponding to residues near the C-terminus of human MUC17
Clone Designation
RM517
Formulation (Request formulation change)
100 μl of protein A-affinity purified antibody
Storage Buffer
PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide
Host
Rabbit
Isotype
IgG
Applications
IHC
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µL

    $411

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Mucin 17 (MUC17) is a member of the mucin family.1 It is composed of an N-terminal tandem repeat domain, which contains O- and N-linked glycosylation sites, two EGF-like domains, a SEA module, a transmembrane region, and a short C-terminal cytoplasmic domain.1,2 MUC17 is alternatively expressed as a membrane-bound- or secreted protein.2 Membrane-bound MUC17 is predominantly expressed in the small intestine and colon by absorptive epithelial cells.1,3 The levels of MUC17 are increased in tumor tissue from patients with colon adenocarcinoma.3 Cayman's MUC17 Rabbit Monoclonal Antibody (Clone RM517) can be used for immunohistochemistry (IHC).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gum, J.R., Jr., Crawley, S.C., Hicks, J.W., et al. MUC17, a novel membrane-tethered mucin. Biochem. Biophys. Res. Commun. 291(3), 466-475 (2002).

    2. Moniaux, N., Junker, W.M., Singh, A.P., et al. Characterization of human mucin MUC17. Complete coding sequence and organization. The Journal of Biological Chemisty 281(33), 23676-23685 (2006).

    3. Krishn, S.R., Kaur, S., Smith, L.M., et al. Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer. Cancer Lett. 374(2), 304-314 (2017).