For immunochemical detection of MGBA
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MGBA Rabbit Monoclonal Antibody (Clone RM519)

Item No. 42785

Product Insert (PDF)
Technical Information
Synonyms
  • Mammaglobin-1
  • Mammaglobin-A
  • MGB1
  • MGBA
  • SCGB2A2
  • Secretoglobin Family 2A Member 2
Immunogen
Peptide corresponding to residues near the N-terminus of human MGBA
Clone Designation
RM519
Formulation (Request formulation change)
100 µl of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
IHC, WB
Cross Reactivity
(+) MGBA
Species Reactivity
(+) Human
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µl

    $411

    Add
    Cayman Chemical
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    Product Description

    Mammaglobin-A (MGBA) is a member of the uteroglobin/Clara cell protein family that is expressed exclusively in the mammary gland.1,2,3 Decreased expression of SCGB2A2, the gene encoding MGBA, is associated with decreased proliferation, migration, and invasion of breast cancer cells in vitro.3 Overexpression of SCGB2A2 is found in most breast cancers, including non-invasive, invasive, and metastatic breast cancers, and has been used as a biomarker for the detection of circulating breast cancer cells and breast cancer metastases.3,2 Cayman’s MGBA Rabbit Monoclonal Antibody (Clone RM519) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gorbokon, N., Timm, P., Dum, D., et al. Mammaglobin-A expression is highly specific for tumors derived from the breast, the female genital tract, and the salivary gland. Diagnostics (Basel) 13(6), 1202 (2023).

    2. Tiriveedhi, V., Sarma, N.J., Subramanian, V., et al. Identification of HLA-A24-restricted CD8+ cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer-associated antigen. Hum. Immunol. 73(1), 11-16 (2012).

    3. Picot, N., Guerrette, R., Beauregard, A.-P., et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol. Carcinog. 55(7), 1150-1162 (2016).