For immunochemical detection of estradiol
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Estradiol Rabbit Monoclonal Antibody (Clone RM343)

Item No. 42799

Product Insert (PDF)
Technical Information
Synonyms
  • E2
  • β-Estradiol
  • 17β-Estradiol
  • 17β-Oestradiol
Immunogen
Estradiol BSA conjugate
Clone Designation
RM343
Formulation (Request formulation change)
100 µl of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Applications
Competitive ELISA and Immunoassays
Cross Reactivity
(+) Estradiol(-) Dehydroepiandrosterone sulfate(-) 17α-estradiol(-) Estriol(-) Estrone(-) Progesterone
Species Reactivity
(Independent) Species
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µl

    $411

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    Product Description

    Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles.1,2 It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle.3,4,5 Plasma levels of estradiol peak during the follicular phase of the menstrual cycle where it stimulates the proliferation of granulosa cells, increases the size of uterine glands, and exerts positive feedback on the hypothalamus, leading to an increase in luteinizing hormone (LH).1,4,5,6 Blood levels of estradiol drop as LH levels increase and trigger ovulation, then rise again during the luteal phase.4 Cayman’s Estradiol Rabbit Monoclonal Antibody (Clone RM343) can be used for competitive ELISA and immunoassay applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Williams, C.J., and Erickson, G.F. Morphology and physiology of the ovary. Endotext [Internet] (2000).

    2. Vance, D.E. Cholesterol and related derivatives. Biochemistry 2nd ed., 725-748 (1988).

    3. Bordini, B., and Rosenfield, R.L. Normal pubertal development: Part I: The endocrine basis of puberty. Pediatr. Rev. 32(6), 223-229 (2011).

    4. Jones, R.E., and Lopez, K.H. Chapter 3 - The Menstrual Cycle. Human Reproductive Biology 51-66 (2014).

    5. Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. Endocrinology and Metabolism 973-1015 (1995).

    6. Christensen, A., Bentley, G.E., Cabrera, R., et al. Hormonal regulation of female reproduction. Horm. Metab. Res. 44(8), 587-591 (2012).