An ionizable cationic lipid
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514O6,10

Item No. 42917

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
bis(2-hexyldecyl) 7,11-diethyl-4,14-bis(3-((2-hexyldecyl)oxy)-3-oxopropyl)-4,7,11,14-tetraazaheptadecanedioate
CAS Number
2863553-06-2
Molecular Formula
C87H172N4O8
Formula Weight
1402.3
Purity
≥95%
Formulation (Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble: ≥10 mg/ml
SMILES
CCCCCCCCC(CCCCCC)COC(CCN(CCC(OCC(CCCCCC)CCCCCCCC)=O)CCN(CCCN(CC)CCN(CCC(OCC(CCCCCCCC)CCCCCC)=O)CCC(OCC(CCCCCCCC)CCCCCC)=O)CC)=O
InChi Code
InChI=1S/C87H172N4O8/c1-11-21-29-37-41-49-58-80(54-45-33-25-15-5)76-96-84(92)62-68-90(69-63-85(93)97-77-81(55-46-34-26-16-6)59-50-42-38-30-22-12-2)74-72-88(19-9)66-53-67-89(20-10)73-75-91(70-64-86(94)98-78-82(56-47-35-27-17-7)60-51-43-39-31-23-13-3)71-65-87(95)99-79-83(57-48-36-28-18-8)61-52-44-40-32-24-14-4/h80-83H,11-79H2,1-10H3
InChi Key
LSTDEAUHCJMJIZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $54

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    5 mg

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    10 mg

    $405

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    25 mg

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    Cayman Chemical
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    Product Description

    514O6,10 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1 LNPs containing 514O6,10 and encapsulating an mRNA reporter traffic to the spleen, lungs, and liver in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Petersen, D.M.S., Weiss, R.M., Hajj, K.A., et al. Branched-tail lipid nanoparticles for intravenous mRNA delivery to lung immune, endothelial, and alveolar cells in mice. Adv. Healthc. Mater. 13(22), e2400225 (2024).