An Analytical Reference Standard
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Parent Compound(s)
23507Difludiazepam
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Nordifludiazepam

Item No. 42920

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Ro 07-3953
Technical Information
Formal Name
7-chloro-5-(2,6-difluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CAS Number
28910-86-3
Molecular Formula
C15H9ClF2N2O
Formula Weight
306.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
ClC1=CC(C(C2=C(F)C=CC=C2F)=NC3)=C(C=C1)NC3=O
InChi Code
InChI=1S/C15H9ClF2N2O/c16-8-4-5-12-9(6-8)15(19-7-13(21)20-12)14-10(17)2-1-3-11(14)18/h1-6H,7H2,(H,20,21)
InChi Key
WENMWXYJTWETRE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Nordifludiazepam (Item No. 42920) is an analytical reference standard categorized as a benzodiazepine.1 Nordifludiazepam is a potential metabolite of difludiazepam (Item No. 23507) based on the published metabolism of midazolam (Item Nos. 19391 | 16193).2 It potentiates ethanol-induced narcosis and has anticonvulsant activity in mice.1 At the time nordifludiazepam (Item No. 42920) was made available for purchase, specific metabolism data had not been published. Contact us if updated information on this molecule is now available. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lemke, T.L., Hester, J.B., and Rudzik, A.D. A new 2,6-difluorobenzodiazepinone. J. Pharm. Sci. 61(2), 275-277 (1972).

    2. Vogt, S.K., Kempf, J., Buttler, J., et al. Desalkylflurazepam found in patients' samples after high-dose midazolam treatment. Drug Test Anal. 5(9-10), 745-747 (2013).