A peptide inducer of SYND1 and collagen XVII
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Acetyl Tetrapeptide-11

Item No. 42985

Technical Information
Formal Name
1-acetyl-L-prolyl-L-prolyl-L-tyrosyl-L-leucine
CAS Number
928006-88-6
Synonyms
  • Ac-Pro-Pro-Tyr-Leu-OH
Molecular Formula
C27H38N4O7
Formula Weight
Purity
≥95%
A solid
Peptide Sequence
Ac-PPYL-OH
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/mlPBS pH 7.2: Sparingly soluble: 1-10 mg/ml
SMILES
O=C([C@H]1N(C([C@@H]2CCCN2C(C)=O)=O)CCC1)N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CC(C)C)C(O)=O)=O
InChi Code
InChI=1S/C27H38N4O7/c1-16(2)14-21(27(37)38)29-24(34)20(15-18-8-10-19(33)11-9-18)28-25(35)22-6-4-13-31(22)26(36)23-7-5-12-30(23)17(3)32/h8-11,16,20-23,33H,4-7,12-15H2,1-3H3,(H,28,35)(H,29,34)(H,37,38)/t20-,21-,22-,23-/m0/s1
InChi Key
KQEQPUBSXXOUGC-MLCQCVOFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Acetyl tetrapeptide-11 is a peptide inducer of syndecan-1 (SYND1) and collagen XVII.1 It increases SYND1 and collagen XVII levels in primary human keratinocytes when used at a concentration of 2.6 µg/ml. Formulations containing acetyl tetrapeptide-11 have been used in skin care cosmetics.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rodrigues, A.-L., Benoit, I., Clarius, T., et alCounteracting ageing phenomena by new pure tetrapeptides with targeted efficacy. J. Appl. Cosmetol. 27(2), 63-71 (2008).