A potential impurity found in commercial preparations of zopiclone
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Research Area

Zopiclone Impurity B

Item No. 43001

Technical Information
Formal Name
6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
CAS Number
43200-81-3
Synonyms
  • RP 29307
Molecular Formula
C11H7ClN4O2
Formula Weight
Purity
≥95%
A solid
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O=C1C2=NC=CN=C2C(N1C3=NC=C(C=C3)Cl)O
InChi Code
InChI=1S/C11H7ClN4O2/c12-6-1-2-7(15-5-6)16-10(17)8-9(11(16)18)14-4-3-13-8/h1-5,10,17H
InChi Key
FUUXOEKDNNWZTR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Zopiclone impurity B is a potential impurity found in commercial preparations of the non-benzodiazepine hypnotic zopiclone.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Han, X., Cheng, F.-J., Di, B., et alIdentification and characterization of new impurities in zopiclone tablets by LC-QTOF-MS. J. Pharm. Biomed. Anal. 199:114056, (2021).