A glucocorticoid
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21-deacetoxy Deflazacort

Item No. 43019

Technical Information
Formal Name
11β-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16β-d]oxazole-3,20-dione
CAS Number
13649-88-2
Molecular Formula
C23H29NO4
Formula Weight
Purity
≥95%
A solid
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
CC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(C)=N2)C)=O
InChi Code
InChI=1S/C23H29NO4/c1-12(25)23-19(28-13(2)24-23)10-17-16-6-5-14-9-15(26)7-8-21(14,3)20(16)18(27)11-22(17,23)4/h7-9,16-20,27H,5-6,10-11H2,1-4H3/t16-,17-,18-,19+,20+,21-,22-,23+/m0/s1
InChi Key
WQUXBQVUVGNOKK-AAZVSSJSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    21-deacetoxy Deflazacort is a glucocorticoid.1 It induces hepatic gluconeogenesis in adrenalectomized rats when administered at a dose of 0.2 mg/kg.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nathansohn, G., Pasqualucci, C.R., Radaelli, P., et alSteroids possessing nitrogen atoms. V. (1) Some pharmacological and chemico-physical aspects of a new class of active corticoids: [17α,16α-d]-oxazolino-steroids. Steroids 13(3), 365-381 (1969).