A non-natural amino acid
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Methoxine

Item No. 43065

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
O-methyl-homoserine
CAS Number
4385-91-5
Synonyms
  • 2-Amino-4-methoxybutanoic Acid
  • NSC 9325
Molecular Formula
C5H11NO3
Formula Weight
133.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): Soluble: ≥ 10 mg/ml
SMILES
COCCC(C(O)=O)N
InChi Code
InChI=1S/C5H11NO3/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChi Key
KFHRMMHGGBCRIV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 mg

    $87

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    100 mg

    $165

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    250 mg

    $261

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    Product Description

    Methoxine is a non-natural amino acid.1 It increases the proliferation of, and glucose consumption in, primary bovine rumen bacteria when used at a concentration of 8 mg/ml. Methoxine (40 g in the diet) increases serum and rumen lipid levels in cattle.2 It has been used as an oxidation-resistant replacement for methionine in the synthesis of radiolabeled peptides.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gil, L.A., Shirley, R.L., and Moore, J.E. Effect of methionine hydroxy analog on growth amino acid content, and catabolic products of glucolytic rumen bacteria in vitro. J. Dairy Sci. 56(6), 757-762 (1973).

    2. Patton, R.A., McCarthy, R.D., and Griel, L.C., Jr. Observations on rumen fluid, blood serum, and milk lipids of cows fed methionine hydroxy analog. J. Dairy Sci. 53(6), 776-780 (1970).

    3. Grob, N.M., Behe, M., von Guggenberg, E., et al. Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates. J. Pept. Sci. 23(1), 38-44 (2017).