A derivative of C14TKL-1
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Product Type

Biochemicals
Peptides

RHRTPMFYGLM-NH2 (trifluoroacetate salt)

Item No. 43089

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(S)-1-(L-arginyl-L-histidyl-L-arginyl-L-threonyl)-N-((S)-1-(((S)-1-(((S)-1-((2-(((S)-1-(((S)-1-amino-4-(methylthio)-1-oxobutan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-4-(methylthio)-1-oxobutan-2-yl)pyrrolidine-2-carboxamide, trifluoroacetate salt
Molecular Formula
C63H98N20O13S2 • XCF3COOH
Formula Weight
1407.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
RHRTPMFYGLM-NH2
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlPBS pH 7.2: Soluble: ≥10 mg/ml
SMILES
O=C([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@H](CCCNC(N)=N)N)=O)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=C(O)C=C4)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCSC.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C63H98N20O13S2.C2HF3O2/c1-35(2)28-45(57(92)76-42(52(65)87)21-26-97-4)75-50(86)33-73-54(89)46(30-38-17-19-40(85)20-18-38)80-58(93)47(29-37-12-7-6-8-13-37)81-55(90)44(22-27-98-5)78-60(95)49-16-11-25-83(49)61(96)51(36(3)84)82-56(91)43(15-10-24-72-63(68)69)77-59(94)48(31-39-32-70-34-74-39)79-53(88)41(64)14-9-23-71-62(66)67;3-2(4,5)1(6)7/h6-8,12-13,17-20,32,34-36,41-49,51,84-85H,9-11,14-16,21-31,33,64H2,1-5H3,(H2,65,87)(H,70,74)(H,73,89)(H,75,86)(H,76,92)(H,77,94)(H,78,95)(H,79,88)(H,80,93)(H,81,90)(H,82,91)(H4,66,67,71)(H4,68,69,72);(H,6,7)/t36-,41+,42+,43+,44+,45+,46+,47+,48+,49+,51+;/m1./s1
InChi Key
DREICYRCNDCNEG-IWKBMRJASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $58

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    5 mg

    $258

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    10 mg

    $458

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    25 mg

    $1,001

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    Product Description

    RHRTPMFYGLM-NH2 is a derivative of the endogenous neurokinin-1 (NK1) receptor agonist C14TKL-1 that contains leucine at position 10 instead of tyrosine.1,2 It contains the typical tachykinin motif FXGLM-NH2.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jiang, Y., Gao, G., Fang, G., et al. PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm. Genome 14(5), 341-349 (2003).

    2. Page, N.M. New challenges in the study of the mammalian tachykinins. Peptides 26(8), 1356-1368 (2005).