An anticancer agent
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Clanfenur

Item No. 43105

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluoro-benzamide
CAS Number
51213-99-1
Synonyms
  • NSC 603108
Molecular Formula
C16H15ClFN3O2
Formula Weight
335.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(NC1=CC=C(C=C1)Cl)NC(C2=C(C=CC=C2F)N(C)C)=O
InChi Code
InChI=1S/C16H15ClFN3O2/c1-21(2)13-5-3-4-12(18)14(13)15(22)20-16(23)19-11-8-6-10(17)7-9-11/h3-9H,1-2H3,(H2,19,20,22,23)
InChi Key
SRLPZQAEBMZCIJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $98

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    10 mg

    $176

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    25 mg

    $344

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    50 mg

    $588

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    Cayman Chemical
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    Product Description

    Clanfenur is an anticancer agent.1 It induces cell death in B16/F10 melanoma cells with a half-maximal inhibitory dose (ID50) value of 1 µg/ml. Clanfenur (800 mg/kg) also increases the number of bone marrow cells, mature and immature neutrophils, and decreases the number of proerythroblasts and normoblast erythrocytes in mice after 42 hours.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hofs, H.P., and McVie, J.G. Effects of benzoylphenyl ureas on growth of B16 melanoma cells in vitro and in vivo. Invest. New Drugs 9(3), 227-232 (1991).

    2. Jenkins, V.K., Juneja, H.S., Ives, K., et al. Effects of diflubenzuron and clanfenur on mouse bone marrow cells. Invest. New Drugs 11(4), 279-289 (1993).