A nucleoside building block
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5'-O-DMT-Thymidine-CE Phosphoramidite

Item No. 43259

Technical Information
Formal Name
3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-thymidine
CAS Number
98796-51-1
Synonyms
  • DMT-dT Phosphoramidite
  • DT-CE phosphoramidite
  • Thymidine phosphoramidite
Molecular Formula
C40H49N4O8P
Formula Weight
Purity
≥98%
A solid
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(NC(C(C)=C5)=O)=O)C[C@@H]4OP(OCCC#N)N(C(C)C)C(C)C
InChi Code
InChI=1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/m0/s1
InChi Key
UNOTXUFIWPRZJX-CEXSRUIHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    5'-O-DMT-Thymidine-CE phosphoramidite is an amine-protected nucleoside building block that has been used in the synthesis of oligodeoxyribonucleotides.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kataoka, M., Kawai, R., and Hayakawa, Y. A facile synthesis of DNA oligomers with modified backbones via the phosphoramidite method without nucleoside base protection. Nucleic Acids Symp. Ser. 42, 105-106 (1999).