A dipeptide intermediate in GSH catabolism
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Cysteinylglycine

Item No. 43262

Technical Information
Formal Name
L-cysteinyl-glycine
CAS Number
19246-18-5
Synonyms
  • Cys-Gly
Molecular Formula
C5H10N2O3S
Formula Weight
Purity
≥85%
A solid
DMSO: Slightly soluble: 0.1-1 mg/mlEthanol: Slightly soluble: 0.1-1 mg/mlPBS pH 7.2: Soluble: ≥10 mg/ml
SMILES
OC(CNC([C@@H](N)CS)=O)=O
InChi Code
InChI=1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)/t3-/m0/s1
InChi Key
ZUKPVRWZDMRIEO-VKHMYHEASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cysteinylglycine is an endogenous dipeptide intermediate in glutathione (GSH) catabolism.1 It is formed from extracellular GSH via hydrolysis or transpeptidation mediated by γ-glutamyl transpeptidase (GGT) and is a cellular source of cysteine and glycine for the formation of GSH.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Griffith, O.W., and Tate, S.S. The apparent glutathione oxidase activity of γ-glutamyl transpeptidase. Chemical mechanism. The Journal of Biological Chemisty 255(11), 5011-5014 (1980).

    2. Zeevalk, G.D., Razmpour, R., and Bernard, L.P. Glutathione and Parkinson’s disease: Is this the elephant in the room? Biomed. Pharmacother. 62(4), 236-249 (2008).