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Monoethyl itaconate is a copolymerization agent.1 It has been used in the generation of copolymeric hydrogels for the formation of methotrexate-containing polymer discs.
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1. Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery. J. Biomed. Mater. Res. B Appl. Biomater. 91(2), 716-726 (2009).