A nucleoside building block
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5'-O-(4,4′-dimethoxytrityl)-2'-Deoxyguanosine(DMF)-CE Phosphoramidite

Item No. 43280

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-[(dimethylamino)methylene]-guanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS Number
330628-04-1
Synonyms
  • DMF-dG-CE Phosphoramidite
  • 5’-O-DMT-2’-Deoxyguanosine(DMF)-CE Phosphoramidite
  • 5'-O-DMT-2'-Deoxyguanosine(DMF)-cyanoethyl Phosphoramidite
  • DMT-dG(DMF)-CE Phosphoramidite
Molecular Formula
C43H53N8O7P
Formula Weight
824.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
COC1=CC=C(C(C(C=C2)=CC=C2OC)(OC[C@@H]3[C@H](C[C@@H](O3)N4C=NC5=C4NC(/N=C/N(C)C)=NC5=O)OP(N(C(C)C)C(C)C)OCCC#N)C6=CC=CC=C6)C=C1
InChi Code
InChI=1S/C43H53N8O7P/c1-29(2)51(30(3)4)59(56-24-12-23-44)58-36-25-38(50-28-45-39-40(50)47-42(48-41(39)52)46-27-49(5)6)57-37(36)26-55-43(31-13-10-9-11-14-31,32-15-19-34(53-7)20-16-32)33-17-21-35(54-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H,47,48,52)/b46-27+/t36-,37+,38+,59?/m0/s1
InChi Key
YRQAXTCBMPFGAN-UNHDIWNRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 g

    $28

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    5 g

    $131

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    10 g

    $220

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    Product Description

    5'-O-DMT-2'-deoxyguanosine(DMF)-CE phosphoramidite is a nucleoside building block.1 It has been used in the synthesis of Cy5-labeled or DBCO-functionalized oligonucleotides, which were conjugated to the surface of nanoparticles for use in the study of large particle partitioning into molecular condensates.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kelley, F.M., Ani, A., Pinlac, E.G., et al. Controlled and orthogonal partitioning of large particles into biomolecular condensates. bioRxiv (2024).