A nucleoside building block
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3’-F-3’-dA(Bz)-2’-phosphoramidite

Item No. 43330

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-3′-fluoro-adenosine, 2′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS Number
2127174-09-6
Molecular Formula
C47H51FN7O7P
Formula Weight
875.9
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly Soluble: 1-10 mg/mlEthanol: Sparingly Soluble: 1-10 mg/ml
SMILES
COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@@H]4[C@@H](F)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](N5C=NC6=C(NC(C7=CC=CC=C7)=O)N=CN=C65)O4
InChi Code
InChI=1S/C47H51FN7O7P/c1-31(2)55(32(3)4)63(60-27-13-26-49)62-42-40(48)39(61-46(42)54-30-52-41-43(50-29-51-44(41)54)53-45(56)33-14-9-7-10-15-33)28-59-47(34-16-11-8-12-17-34,35-18-22-37(57-5)23-19-35)36-20-24-38(58-6)25-21-36/h7-12,14-25,29-32,39-40,42,46H,13,27-28H2,1-6H3,(H,50,51,53,56)/t39-,40-,42-,46-,63?/m1/s1
InChi Key
WTXSTLCSPVTJTM-MSIRFHFKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $54

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    10 mg

    $103

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    25 mg

    $229

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    50 mg

    $405

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    Product Description

    3'-F-3'-dA(Bz)-2'-phosphoramidite is an amine-protected nucleoside building block that has been used in the synthesis of cyclic dinucleotides.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Song, Y., Li, A., and Chen, X. Cyclic di-nucleotides as stimulator of interferon genes modulators. WO2019/043634A2, (2019).