A nucleoside building block
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N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-3’-deoxy-3’-fluoro-β-D-xylofuranosyl Cytidine-2’-CED Phosphoramidite

Item No. 43370

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-3-fluoro-β-D-xylofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide
CAS Number
1555759-30-2
Molecular Formula
C46H51FN5O8P
Formula Weight
851.9
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Slightly Soluble: 0.1-1 mg/ml
SMILES
O=C(NC(C=CN1[C@@H]([C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H]2F)O[C@@H]2COC(C(C=C3)=CC=C3OC)(C(C=C4)=CC=C4OC)C5=CC=CC=C5)=NC1=O)C6=CC=CC=C6
InChi Code
InChI=1S/C46H51FN5O8P/c1-31(2)52(32(3)4)61(58-29-13-27-48)60-42-41(47)39(59-44(42)51-28-26-40(50-45(51)54)49-43(53)33-14-9-7-10-15-33)30-57-46(34-16-11-8-12-17-34,35-18-22-37(55-5)23-19-35)36-20-24-38(56-6)25-21-36/h7-12,14-26,28,31-32,39,41-42,44H,13,29-30H2,1-6H3,(H,49,50,53,54)/t39-,41+,42-,44-,61?/m1/s1
InChi Key
BYZDYCULMRMWKL-OEJVQKCDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $28

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    5 mg

    $131

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    10 mg

    $248

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    25 mg

    $413

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    Product Description

    N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoro-β-D-xylofuranosyl cytidine-2'-CED phosphoramidite is a nucleoside building block that has been used in the synthesis of double-stranded RNA (dsRNA).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rajeev, K.G., and Manoharan, M. Modified RNAI agents. (2015).