An adenosine A1 receptor agonist
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SDZ-WAG 994

Item No. 43521

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-cyclohexyl-2′-O-methyl-adenosine
CAS Number
130714-47-5
Molecular Formula
C17H25N5O4
Formula Weight
363.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Soluble: ≥ 10 mg/ml
SMILES
O[C@H]1[C@@H](OC)[C@H](N2C=NC3=C(NC4CCCCC4)N=CN=C32)O[C@@H]1CO
InChi Code
InChI=1S/C17H25N5O4/c1-25-14-13(24)11(7-23)26-17(14)22-9-20-12-15(18-8-19-16(12)22)21-10-5-3-2-4-6-10/h8-11,13-14,17,23-24H,2-7H2,1H3,(H,18,19,21)/t11-,13-,14-,17-/m1/s1
InChi Key
JAKAFSGZUXCHLF-LSCFUAHRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $32

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    5 mg

    $152

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    10 mg

    $288

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    25 mg

    $678

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    Product Description

    SDZ-WAG 994 is an adenosine A1 receptor agonist.1 It selectively binds to adenosine A1 receptors over adenosine A2 receptors (Kds = 19.95 and 25,109 nM, respectively) and induces adenylate cyclase activity in rat adipocyte membranes (EC50 = 398 nM). In vivo, SDZ-WAG 994 (0.14-1.4 µmol/kg) induces hypotension and bradycardia in spontaneously hypertensive rats.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wagner, H., Milavec-Krizman, M., Gadient, F., et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug Dev. Res. 34(3), 276-288 (1995).